Which supplements actually work?
Describe what you want to improve. We match it against 69 meta-analyses and systematic reviews and rank supplements by the strength of the evidence, with doses, side effects and drug interactions.
Browse by goal
Fall asleep faster
Trouble getting to sleep at night.
Sleep quality
Waking up unrefreshed or sleeping lightly.
Jet lag
Adjusting to a new time zone after travel.
Stress & anxious feelings
Feeling stressed, tense, or on edge.
Low mood
Feeling down or low on motivation.
Focus & alertness
Staying sharp, attentive, and awake.
Memory
Learning, recall, and mental performance.
Energy & fatigue
Feeling tired or low on energy.
Muscle & strength
Building muscle and strength with training.
Endurance & performance
Running, cycling, and high-intensity performance.
Joint comfort
Stiff or achy joints, especially knees.
Regularity
Infrequent or hard bowel movements.
Gut comfort
Bloating, IBS-type symptoms, or diarrhea from antibiotics.
Colds & immune support
Catching fewer colds or recovering faster.
Heart health markers
Blood pressure, triglycerides, and cholesterol.
Skin
Skin hydration and elasticity.
Nausea
Queasiness, including morning sickness.
Bone health
Maintaining bone strength as you age.
Evidence first
Every recommendation links to peer-reviewed meta-analyses on PubMed.
Safety built in
We check common drug interactions and pregnancy safety, and flag when to see a doctor.
Independent ranking
Rankings are based on evidence only. Affiliate links never change the order.