Start with the basics
- Daily sunscreen and not smoking have the strongest evidence for skin aging.
Talk to a healthcare professional first
This information is for education only and is not medical advice, diagnosis, or treatment. Supplements can interact with medications and health conditions. Check with your doctor or pharmacist before starting anything, especially if you take medication, are pregnant or breastfeeding, or have a health condition. These statements have not been evaluated by the FDA; supplements are not intended to diagnose, treat, cure, or prevent any disease.
Ranked by strength of evidence
No supplements with reasonable evidence yet.
Popular, but the evidence is weak
- DCollagen peptides— Some meta-analyses report improved skin hydration and elasticity, but a 2025 meta-analysis found no effect in studies without industry funding or in high-quality studies — benefits appeared only in industry-funded and lower-quality trials.
When to see a doctor
- You notice a changing mole or a new, non-healing skin lesion.