Vitamin D
CLimited evidenceVitamin D alone did not reduce fractures in community-dwelling adults; combined calcium + vitamin D showed a small reduction in some analyses, mainly in older or institutionalized people.
- Dose used in studies
- 800–1,000 IU/day, usually with calcium
- Time to effect
- Months to years
- Most relevant for
- Older adults at fracture risk, together with calcium
Studies (3)
- Vitamin D and Calcium for the Prevention of Fracture: A Systematic Review and Meta-analysis — JAMA Netw Open, 2019 · Meta-analysis · PMID 31860103
- Association Between Calcium or Vitamin D Supplementation and Fracture Incidence in Community-Dwelling Older Adults: A Systematic Review and Meta-analysis — JAMA, 2017 · Meta-analysis · PMID 29279934
- Calcium, vitamin D, or combined supplementation to prevent fractures and falls: systematic review and meta-analysis — BMJ, 2026 · Meta-analysis · PMID 42161415